, BURHANFATIH KOÇYIĞIT2
, SAVAŞ GÜRSOY2
Ceyhan Community Health Center, Adana, Turkey, 2
Gaziantep University Medical Faculty, Department of Physical Medicine and
Rehabilitation, Gaziantep, Turkey
Introduction: Fibromyalgia syndrome (FMS) is a chronic syndrome characterized by widespread musculoskeletal pain, tender
points and fatigue. There are several studies suggesting a possible relationship between musculoskeletal pain and vitamin D deficiency.
In this study, we aimed to compare serum vitamin D levels between fibromyalgia patients and control groups and investigate
the relationship between vitamin D and clinical findings on patients with fibromyalgia syndrome.
Materials and methods: This case control study enrolled 79 women with fibromyalgia who fulfilled the American College of
Rheumatology 1990 criteria and 80 healthy women. All subjects were evaluated with vitamin D and other biochemical markers. The
patients were divided into three groups based on their serum vitamin D levels (normal, insufficient, deficient). Visual analogue scale
and fibromyalgia impact questionnaire were used to evaluate the patients with FMS.
Results: Mean serum vitamin D levels were lower in the FMS group than in the controls (12.99±8.37 ng/ml vs.16.05±9.42 ng/ml,
p=0.037). Vitamin D level was significantly negative correlated with visual analogue scale, tender point count and fibromyalgia
impact questionnaire ( p=0.000, r=-0.578; p=0.001, r=-0.361; p=0.000, r=-0.621).
Conclusion: It was concluded that vitamin D deficiency may be related to the clinical findings in patients with FMS.
Fibromyalgia, vitamin D, pain, Turkey