Authors

Yi Shen, Jun Li, Shen Zhang, Min Yang#

Departments

Department of Critical Medicine, Shanghai Chest Hospital, Shanghai Chest Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, PR China

Abstract

Objective: To analyse the value of SIRS, SOFA, and qSOFA scores in sepsis expression and prognosis evaluation.

Method: 173 adult patients who were admitted to the ICU in our hospital between August 2017 and December 2019 were selected. 118 patients with an infection or a suspected infection were selected as the infection group, and 55 patients were selected as the non-infection group. The general clinical data, vital signs, and laboratory indicators of all patients were collected, and the SIRS, SOFA, and qSOFA scores were calculated according to the clinical data of the patients. A ROC curve was used to analyse the diagnostic and prognostic value of the three scores for sepsis patients.

Results: The age, body temperature, and PCT level of the infected group were significantly higher than those of the non-infected group, and the ratio of PaO2/FiO2 was significantly lower than that of the non-infected group (P<.05); The SIRS, qSOFA, and SOFA scores of the infected group were significantly higher than those of the non-infected group (P<.01); ROC curve analysis showed that SIRS, qSOFA, and SOFA scores were significantly higher than those of the non-infected group (P<.01). The area under the curve (AUC) of the diagnostic prediction of sepsis was 0.627, 0.658 and 0.771, respectively. SOFA score was better than SIRS and qSOFA score in diagnosing sepsis. The AUC of SIRS, qSOFA, and SOFA scores for sepsis prognosis were 0.650, 0.668 and 0.748, respectively. SOFA scores were better than SIRS and qSOFA scores in evaluating the prognosis of sepsis.

Conclusion: The SOFA score of patients with sepsis in the ICU can better predict the occurrence and prognosis of sepsis. SIRS≥3, SOFA≥6 and qSOFA≥2 of patients with sepsis in ICU can accurately evaluate the diagnosis and prognosis of patients with sepsis.

Keywords

SIRS, SOFA, qSOFA score, sepsis, prognostic evaluation, clinical.

DOI:

10.19193/0393-6384_2020_3_257