Authors

Jianxin He*, Liping Yan**, Jia Zhu***, Aiyun Zhou*

Departments

*Department of ultrasound medicine, The First Affiliated Hospital, Nanchang University, Nanchang, China - **Department of Breast surgery, The Third Hospital of Nanchang, Nanchang, China - ***Department of General surgery, The First Affiliated Hospital, Nanchang University, Nanchang, China

Abstract

Objective: To explore the influence of risk factors on arterial stiffness, we study the correlation between carotid pulse wave velocity and risk factors of diabetes in diabetic population.

Methods: The patients with type II diabetes who were hospitalized in our hospital were analyzed retrospectively. In all cases, the carotid Impedimenta thickness was measured by the automatic tracing method of the ultrasound instrument, and the plaque of the carotid artery was evaluated by two-dimensional image. The parameters of the two-sided carotid PWV were measured by the ultra-fast pulse wave technology. Serum biochemical examination were collected and measured by Biochemical automatic analyzer; the course of disease, medication and complications were obtained through clinical medical records. The multiple linear regression model was used to analyze the correlation between the main risk factors of diabetic patients and carotid PWV value.

Results: Data from 22 diabetics were collected, the ratio of males to females was 1.2:1. The age range was 44-82 years-old. The parameters of PWV of bilateral common carotid artery ( the left common carotid artery PWV-BS (LCCA PWV-BS), the left common carotid artery PWV-ES(LCCA PWV-ES), the right common carotid artery PWV-BS (RCCA PWV-BS) and the right common carotid artery PWV-ES (RCCA PWV-ES )) were analyzed with four times of multiple linear regression analysis , the results are as follows: There were linear correlations between LCCA PWV-BS and LCCA PWV-ES , R:0.611, P=0.003; between LCCA PWV-BS and two variable of LCCA PWV-ES and body mass index (BMI), R:0.754, P< 0.001; there was a linear correlation between LCCA PWV-ES and two variable of LCCA PWV-BS and BMI , R: 0.773, P< 0.001; there was a linear correlation between RCCA PWV-ES and course of disease, R: 0.503, P = 0.017. 

Conclusion: In this study, we found that the main risk factors of arteriosclerosis in type II diabetic patients are obesity and onset time. The main valuable parameter of carotid ufPWV to evaluate arteriosclerosis is the left common carotid artery PWV-BS and the right common carotid artery PWV-ES.

Keywords

Arteriosclerosis, Diabetes Mellitus, Type 2, Carotid artery Stiffness, Pulse wave velocity, Ultrasonography.

DOI:

10.19193/0393-6384_2020_3_332