Yaqing Zhu, Yeping Min#


Emergency Department, the Affiliated Changzhou No.2 People’s Hospital of Nanjing Medical University, Changzhou 213000, China


Objective: To analyze the relationship between the NEW-TOAST classification, intravenous thrombolysis in acute stroke, and related auxiliary experience.

Methods: A total of 62 patients with acute stroke who were admitted to the Second People’s Hospital of Changzhou from January 2013 to August 2014 were selected and treated with recombinant human tissue plasminogen activator (rt-PA) thrombolytic therapy within 4.5 hours of onset. According to the NEW-TOAST classification, 30 cases of atherosclerotic stroke (AT) and 32 cases of cardiac embolism (CE) were divided into two groups. The prognosis of patients treated with intravenous at-PA thrombolytic therapy was compared.

Results: After intravenous thrombolysis, there were two cases of bleeding transformation and zero cases of death in the AT group, and three cases of bleeding transformation and one case of death in the CE group. There was no statistically significant difference between the two groups (P>0.05). However, comparison of National Institutes of Health Stroke Scale (NIHSS) scores after two weeks showed that NIHSS scores in the AT group were significantly lower than those in the CE group (11.9±1.9 vs 13.2±2.0, P = 0.010).

Conclusion: The prognosis of venous thrombolysis in ischemic stroke is closely related to the NEW-TOAST classification. Thrombolytic therapy for atherosclerotic stroke has a good prognosis, and actively cooperate with doctors in the process of thrombolysis, which is of important clinical significance for monitoring the patients’ condition changes and blood pressure.


Stroke, thrombolysis, auxiliary.