Jun Fang#, Yongliang Jiang, Bo Huang, Wenjie Tong


Department of Neurosurgery, Shanghai Songjiang District Central Hospital, Shanghai, 201600, China


Objective: To investigate the changes of hs-CRP and NSE levels in patients with cerebral haemorrhage, and the correlation with neurological deficits and bleeding volume.

Methods: A total of 218 people were included in the study. One hundred and forty-four patients with acute cerebral haemorrhage were selected for the experimental group, and 74 healthy individuals, who underwent a physical examination, for the control group. The hs-CRP and NSE were measured, and the correlation between these indicators and the neurological deficit or the amount of bleeding was analysed.

Results: Compared with the control group, serum hs-CRP and NSE levels in the experimental group were significantly increased. The amount of bleeding and neurological deficit were positively correlated with hs-CRP and NSE (P<0.05).

Conclusion: The levels of hs-CRP and NSE in patients with cerebral haemorrhage are elevated and may indicate the severity of brain injury.


Neuron-specific enolase, hypersensitive C-reactive protein, cerebral haemorrhage.