FRANCESCA DI SERIO*, ROBERTO LOVERO*, DONATO D’AGOSTINO**, LUCIA NISI*, GIUSEPPE MIRAGLIOTTA***, RENATO CONTINO*, ADRIAN MAN****, MARCO MATTEO CICCONE*****, LUIGI SANTACROCE******
*Clinical Pathology Service, University Hospital “Policlinico”, Bari, Italy -
**Dept. of Emergency and Organ Transplantations, Sect. of Cardiac Surgery, University of Bari, Italy -
***Interdisciplinary Dept. of Medicine. Sect. of Microbiology and Virology, University of Bari, Italy -
****Microbiology Lab., University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures, Romania -
*****Dept. of Emergency and Organ Transplantation, Sect. of Cardiology, University of Bar, Italy -
******Ionian Dept. & Microbiology and Virology Service, University of Bari, Italy
Sepsis, the systemic inflammatory response to infection, is the most common cause of death in people hospitalized in intensive care units (ICU). Early diagnosis of infection is crucial to the appropriate management of sepsis, with early antibiotic administration consistently resulting in improved outcomes.
The purpose of this study, although preliminary, was to determine whether vitamin D levels correlate with procalcitonin (PCT) and C-reactive protein (CRP) levels in 59 septic patients, with positive emocoltures.
This study is also aimed to point out new possible diagnostic protocols identifying potential biomarkers for the diagnosis of sepsis, defined according to literature data.
sepsis, emocoltures, vitamin D, procalcitonin, C-reactive protein.